Skin barrier support is one of the biggest emphases for 2026. Harsh actives are out, and nourishing ingredients like ceramides, hyaluronic acid and glycerin are in.
Gone are the days of slathering on stressing formulas packed with harsh active ingredients. Ceramide serums are leading a revolution in our skincare habits. Our bathroom shelves should now be lined with simplified solutions comprising impactful, nourishing ingredients that restore hydration.
Vogue’s top ceramide serums at a glance:
Winter weather, central heating and environmental factors like pollution can all compromise the skin barrier – as well as the aforementioned harsh actives, including excessive exfoliants, retinol used incorrectly, and high-concentration vitamin C. All the above can lead to dehydration, dullness, irritation and sensitised skin, causing the complexion to cry out for care, love and attention. That’s where a ceramide serum comes in.
“Ceramides are naturally occurring lipids that make up a large part of the skin barrier,” says dermatologist Dr Alexis Granite. “You can think of them as part of the ‘mortar’ that holds skin cells together. Their job is to keep water in and potential irritants out.” Contained in serum form, they can counteract the aggressive nature of other actives like retinol or treat the complexion to some sought-after hydration.
- Jump to the product reviews
- What exactly are ceramides, and how do they function in the skin barrier?
- Are ceramides better delivered in serums, creams, or lotions?
- Which skin types benefit most from ceramide serums?
- When should a ceramide serum be applied in a routine? Can it be layered with actives like retinoids, acids, or vitamin C?
- Is a serum worth it compared to a ceramide-rich moisturiser?
- Meet the expert
Scroll on to decode everything you need to know about the emerging skincare hero as well as the top formulas to add to your skincare routine.
FAQs
What exactly are ceramides, and how do they function in the skin barrier?
According to dermatologist Dr Alexis Granite, “When ceramide levels are healthy, skin stays hydrated, resilient and calm. When they’re depleted, which can happen with over-cleansing, over-exfoliation, stress, weather change and inflammatory skin conditions, the barrier weakens, and skin can become dry, sensitive and reactive.”
Are ceramides better delivered in serums, creams or lotions?
“Ceramides work well in different textures, but delivery does matter,” reveals the expert. “Creams and lotions are ideal for sealing and maintaining the barrier because they usually combine ceramides with emollients and occlusives that reduce water loss.” As for serums, she says, they “are useful when the barrier is compromised, and you want to deliver ceramides early in your routine in a lightweight, fast-absorbing format.”
Which skin types benefit most from ceramide serums?
The beauty of ceramide serums is that they will, generally speaking, work for all skin types. “Ceramide serums are particularly beneficial for sensitive skin, eczema-prone skin, rosacea-prone skin and anyone dealing with dryness, irritation and/or post-procedure recovery,” confirms Dr Granite. “They’re also helpful for people using active ingredients who want to strengthen their barrier without adding weight or congestion.”
When should a ceramide serum be applied in a routine? Can it be layered with actives like retinoids, acids, or vitamin C?
“A ceramide serum should be applied after cleansing and before moisturiser and SPF,” says Dr Granite. “Think of it as laying down the building blocks of the barrier before you seal everything in. A ceramide serum can absolutely be layered with actives like retinoids, acids or vitamin C. In fact, pairing ceramides with actives often improves tolerance and reduces irritation. I usually recommend applying actives first, then following with a ceramide serum, and finishing with a moisturiser to lock everything in.”
Is a serum worth it compared to a ceramide-rich moisturiser?
This depends says the expert. “Whether a ceramide serum is “worth it” compared to a ceramide-rich moisturiser depends on your skin and routine. If your skin is generally balanced and you prefer simplicity, a well-formulated ceramide moisturiser may be enough. If your barrier is compromised, you’re using stronger actives, or you’re prone to sensitivity, a serum can offer more targeted support.”
Meet the expert
- Dr Alexis Granite is a dual-board certified dermatologist and co-founder of skincare-body brand Joonbyrd







